Ercument Dirice, PhD




Update: May 1, 2014


  • Personal
  • Education
  • Work Experience
  • Courses
  • Memberships
  • Publications

    Publications in Peer-Reviewed Journals (reverse chronology)

    1. Teo AK, Valdez IV, Dirice E, Kulkarni RN. Comparable generation of Activin-induced definitive endoderm via additive Wnt or BMP signaling in absence of serum. Stem Cell Reports 2014 (In press) Pubmed logo
    2. Winnay JN, Dirice E, Liew CW, Kulkarni RN, Kahn CR. p85 alpha deficiency protects beta-cells from endoplasmic reticulum stress-induced apoptosis. PNAS. 2014 Pubmed logo
    3. Dirice E, Kahraman S, Jiang W, El Ouaamari A, De Jesus D, Teo A, Hu J, Kawamori D, Gaglia J, Mathis D, Kulkarni RN, Soluble factors secreted by T-cells promote β-cell proliferation. Diabetes 2013 Pubmed logo                                                                           
    4. El Ouaamari A, Kawamori D, Dirice E, Liew CW, Shadrach JL, Hu J, Katsuta H, Hollister-Lock J, Qıan WJ, Wagers AJ, Kulkarni RN. Liver-derived systemic factors drive β cell hyperplasia in insulin-resistant states. Cell Rep. 2013 Pubmed logo
    5. Teo AK, Windmueller R, Johansson BB, Dirice E, Njolstad PR, Tjora E, Raeder H, Kulkarni RN. Derivation of Human Induced Pluripotent Stem Cells from Patients with Maturity Onset Diabetes of the Young. J Biol Chem. 2013 Pubmed logo
    6. Dirice E, Kahraman S, Elpek GO, Aydin C, Balci MK, Omer A, Sanlioglu S, Sanlioglu AD. TRAIL and DcR1 are differentially regulated in the pancreatic islets of STZ vs CY-applied NOD mice. Exp. Diabetes Res.  2011  Pubmed logo
    7. Kahraman S, Dirice E, Hapil FZ, Ertosun MG, Ozturk S, Griffith TS, Sanlioglu S and Sanlioglu AD. Tracing of xenogeneic islet graft survival by way of in vivo fluorescence imaging. Diabetes Metab. Res. 2011 Sep;27(6):575-83. Pubmed logo
    8. Kahraman S,  Dirice E, Sanlioglu AD, Yoldas B, Bagci H, Erkilic M, Griffith TS, Sanlioglu S. In vivo fluorescence imaging is well-suited for the monitoring of adenovirus directed transgene expression in living organisms. Mol Imaging Biol. 2010 Jun;12(3):278-85. Pubmed logo
    9. Dirice E, Sanlioglu AD, Kahraman S, Ozturk S, Balci MK, Omer A, Griffith TS and Sanlioglu S. Adenovirus mediated TRAIL gene (Ad5hTRAIL) delivery into pancreatic islets prolongs normoglycemia in STZ-induced diabetic rats. Human Gene Therapy. 2009 Oct;20(10):1177-89. Pubmed logo
    10. Sanlioglu AD, Dirice E, Elpek O, Korcum AF, Ozdogan M, Suleymanlar I, Balci MK, Griffith TS, Sanlioglu S.  High TRAIL Death Receptor-4 (DR4) and Decoy Receptor-2 (DcR2) expression correlates with significant cell death in pancreatic ductal adenocarcinoma (PDAC) patients.  Pancreas 2009 Mar;38(2):154-60. Pubmed logo
    11. Sanlioglu AD, Dirice E, Elpek O, Korcum AF, Balci MK, Omer A, Griffith TS, Sanlioglu S. High levels of endogenous tumor necrosis factor-related apoptosis-inducing ligand expression correlate with increased cell death in human pancreas. Pancreas 2008 May;36(4):385-93. Pubmed logo
    12. Sanlioglu AD, Griffith TS, Omer A, Dirice E, Sari R, Altunbas HA, Balci MK, Sanlioglu S.  Molecular mechanisms of death ligand-mediated immune modulation: a gene therapy model to prolong islet survival in type 1 diabetes. J Cell Biochem 2008 June1;104(3):710-20. Pubmed logo
    13. Karauzum SB, Yasar D, Dirice E, Imir N, Luleci G, Ozes ON.  Lack of BCL-2 confers interferon-alpha sensitivity to B-cell lymphomas. Growth Factors. 2007 Apr;25(2):94-100. Pubmed logo
    14. Koksal IT, Yasar D, Dirice E, Usta MF, Karauzum S, Luleci G, Baykara M, Sanlioglu S.  Differential PTEN protein expression profiles in superficial versus invasive bladder cancers. Urol Intl  2005 75(2):102-6. Pubmed logo
    15. Sanlioglu AD, Dirice E, Aydin C, Erin N, Koksoy S, Sanlioglu S. Surface TRAIL decoy receptor-4 expression is correlated with TRAIL resistance in MCF7 breast cancer cells. BMC Cancer 2005 May 5(1):54. Pubmed logo
    16. Koksal T, Dirice E, Yasar D, Sanlioglu AD, Ciftcioglu A, Gulkesen KH, Ozes NO, Baykara M, Luleci G, Sanlioglu S. The assessment of PTEN tumor suppressor gene in combination with Gleason scoring and serum PSA to evaluate progression of prostate carcinoma. Urol Oncology  2004 July-Aug 22(4):307-312. Pubmed logo

    Books and Chapters

    1. Dirice E and Kulkarni RN. Pathways underlying beta-cell regeneration in type1, type2 and gestational diabetes. Landes Bioscience. Cell Growth Factors. 2011 ISBN: 978-1-58706-338-1 landes_logo 
  • Research Interest / Experience